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From251US$ /night
Check-in
12Jan2026Select date
Check-out
13Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

167 West Main Street, Lexington, Kentucky, United States, 40507
-
Close to the Explorium
Great
8.2
8.7
/10
4.5
4.2
/5

Located merely 6 minutes' walk from Gratz Park, the contemporary 21C Museum Hotel Lexington offers 85 rooms with views of the city. The 4-star smoke-free hotel is proud to feature a ballroom, approximately 2 km from Lexington Cemetery.

Location

This boutique-style hotel is within 10 minutes' drive of Whitaker Bank Ballpark Stadium, while the Loudoun House is nearly 25 minutes' walk away. The 21C Museum Hotel Lexington is also situated within reach of the fourteen - room Mary Todd Lincoln House.

There is Transit Center High Street bus stop 750 metres from the accommodation.

Rooms

All of the non-smoking rooms are appointed with a multi-channel television along with an espresso machine, and some of them include a dressing room and a seating area. Guests will make use of a hair dryer and a shower cap in the private bathrooms equipped with a separate toilet and a shower.

Eat & Drink

Also, 21C Museum Hotel Lexington features a lounge bar. Offering American dishes, Sawyer's Downtown lies steps away from this Lexington hotel.

Leisure & Business

The property provides temporary art galleries and a ballroom to make your stay as enjoyable as possible. The hotel invites guests to join yoga classes held in a fitness club. Business travellers will make use of a xerox and a work desk offered at meeting rooms and a 24-hour business centre on site.

“What strikes me most is its commitment to local sourcing, mirrored in Lockbox's regional cuisine and the sustainable ethos throughout. The integration of contemporary art isn't just decoration; it reshapes the experience within a historic building, turning events and stays into immersive encounters. It seems a place where conscience meets culture, just steps from Lexington's heart.”
Hotel logo
James DavidEditor-in-Chief at Dogfriendly-hotels
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Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
City Queen Room
2 persons
22 m² 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
33 m² 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
40 m² 
1 King-size bed
Shower
Coffee machine
Click button to see more rooms
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Rates & availability calendar

See current prices and availability for your chosen dates!

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Free Wi-Fi in public areas
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Dining Onsite

At 21C Museum Hotel Lexington, a culinary adventure awaits within the vibrant walls of Lockbox, offering a delightful twist on American classics, as well as inviting local flavors. Each dining experience is carefully crafted to cater to a variety of dietary preferences, ensuring satisfaction for every guest.
21C Museum Hotel Lexington Restaurant photo

Lockbox

American, Local
Ambiance
A contemporary setting that embraces both modern art and warm hospitality, perfect for gatherings with friends or intimate dinners.
Key Offerings
Indulge in a menu that honors local ingredients with options catering to vegetarian, vegan, gluten-free, and dairy-free diets. Enjoy a comforting breakfast to start your day or savor a thoughtfully curated dinner that celebrates regional flavors.
Reservation
Recommended
Open for breakfast Wednesday to Sunday and dinner Wednesday to Saturday; specific hours vary by day.

Hotel location

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
460 m
Museum
Hunt-Morgan House
460 m
Event hall
Lexington Convention Center
440 m
Theatre
Kentucky Theatre
360 m
440 W Short St
Explorium
450 m
University
University of Kentucky
90 m
Park
Triangle Park
340 m
Church
St Paul the Apostle Catholic Church
430 m
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
260 m
Shopping Area
Victorian Square Shoppes
340 m
Square
Phoenix Park
180 m
Gallery
Limestone Blue
130 m
Lexington Financial Center
Isaac Murphy Memorial Art Garden
140 m
Gallery
Pam Miller Downtown Arts Center
220 m
Gallery
ArtsPlace
240 m
7285 Huron Street
Huron Street Gallery
250 m
Gratz Park
490 m
Restaurants
Bourbon on Rye
70 m
115 W Main St
Corto Lima
180 m
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
120 m
163 West Short Street
Bluegrass Tavern
150 m
115 Cheapside
Horse And Jockey
190 m
131 Cheapside
Buddha Lounge
190 m
109 N Mill St
Explore Lexington
Nearby Activities and Attractions
Top Attractions
Activities
Dining
Entertainment
Rupp Arena
Rupp Arena
6 minutes' walk
Home to sports events and concerts, Rupp Arena hosts notable performances and games, making it a cultural hub.
Mary Todd Lincoln House
Mary Todd Lincoln House
9 minutes' walk
The historic home of Mary Todd Lincoln provides insights into her life and the Civil War era, with guided tours available.
Thoroughbred Park
Thoroughbred Park
12 minutes' walk
Showcases Kentucky's thoroughbred racing heritage, featuring bronze sculptures and a serene atmosphere for relaxing strolls.
University of Kentucky Art Museum
University of Kentucky Art Museum
13 minutes' walk
Offers notable collections of American and European art. Free admission on Wednesdays makes it accessible for all.
Hiking at McConnell Springs
5 minutes' drive
A nature reserve with trails and historical features, ideal for scenic hikes and relaxing moments in nature.
Live Music at Manchester Music Hall
15 minutes' walk
A dynamic venue hosting various live performances. Enjoy a range of genres in an intimate setting.
Bourbon on Rye
Bourbon on Rye
1 minute' walk
Features a cozy atmosphere serving classic Southern dishes with a twist and a notable bourbon selection.
Corto Lima
Corto Lima
3 minutes' walk
Known for vibrant, spicy dishes inspired by Latin America, it offers a lively dining experience with fresh ingredients.
School Sushi
School Sushi
2 minutes' walk
Offers innovative sushi and Asian fusion dishes in a casual setting, perfect for a quick and delicious meal.
Kentucky Theatre
Kentucky Theatre
5 minutes' walk
A historic theater showcasing classic films and local events, creating a nostalgic and cultural entertainment experience.
WoodSongs Old-Time Radio Hour
WoodSongs Old-Time Radio Hour
10 minutes' walk
Features live performances focusing on Americana music, providing a family-friendly atmosphere for all ages.
Local transport and travel tips
City Centre
Lexington5 min  ·  400 m
Airports
Blue Grass Airport (LEX)21 min  ·  13.7 km
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in public areas for free.
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
15
Number of rooms:
85
FAQs
About 21C Museum Hotel Lexington
What are the check-in and check-out times at 21C Museum Hotel Lexington?
Check-in is at 16:00 and check-out is by 11:00.
How far is 21C Museum Hotel Lexington from Blue Grass Airport?
The hotel is located 9 km from Blue Grass Airport, approximately a 20-minute drive.
What dining options are available at 21C Museum Hotel Lexington?
The hotel features Lockbox restaurant and a bar/lounge area for dining and drinks.
What amenities are provided in the rooms at 21C Museum Hotel Lexington?
Rooms include air conditioning, a flat-screen TV, a desk, a safety deposit box, and a private bathroom.
Is there a fitness center available at 21C Museum Hotel Lexington?
Yes, the hotel offers a fitness center and yoga classes for guests.
What nearby attractions can be found close to 21C Museum Hotel Lexington?
Nearby attractions include Hunt-Morgan House (0.5 km), Lexington Convention Center (0.5 km), and Rupp Arena (0.5 km).
Does 21C Museum Hotel Lexington provide any business services?
The hotel has a business center and offers meeting rooms for business needs.

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